PGT
Preimplantation Genetic Testing (PGT)
PGT is an advanced fertility technique used along with IVF to identify genetic or chromosomal abnormalities in embryos before implantation. It helps ensure the transfer of genetically healthy embryos, improving pregnancy outcomes and reducing the risk of inherited disorders.
Indications
- Couples with known genetic disorders
- Recurrent IVF failure
- Recurrent pregnancy loss
- Advanced maternal age
- Previous child with genetic or chromosomal abnormalities
- Repeated implantation failure
Process
- IVF Procedure: Eggs are retrieved and fertilized in the laboratory
- Embryo Development: Embryos are cultured until day 5 (blastocyst stage)
- Embryo Biopsy: A few cells are carefully removed from each embryo
- Genetic Testing: Biopsied cells are tested for genetic or chromosomal defects
- Embryo Selection: Only genetically healthy embryos are selected
- Embryo Transfer: Chosen embryo is transferred into the uterus
- Embryo Freezing: Remaining healthy embryos may be frozen for future use
Success Rate
- Improves implantation and pregnancy rates
- Reduces miscarriage risk significantly
- Success depends on age, embryo quality, and genetic condition
Follow-ups
- Hormonal support after embryo transfer
- Pregnancy test after 12–14 days
- Ultrasound confirmation of pregnancy
- Genetic counseling if required
Risks & Complications
- Minimal risk to embryo when performed by experts
- Slight chance of inconclusive results
- Emotional and financial considerations
- Rare risk of embryo damage
Benefits of ICSI
- Reduces risk of genetic disorders
- Increases chances of healthy pregnancy
- Lowers miscarriage rates
- Helps informed decision-making for embryo transfer
